Current Meridian deployment offers an existing domain or a new domain. Older releases limited the workflow to new subdomains. Check the choices actually offered before planning the destination.
The current documented limit is four apps per cPanel account. A new domain created for an app cannot be renamed after deployment. Choose its name deliberately.
Deleting an app is irreversible and may also remove an app-only domain. Preserve code, configuration, and data and read How to Delete a Meridian Node.js App Safely before freeing an application slot.
Documentation for this guidance: docs.cpanel.net — deploy a website with nodejs; docs.cpanel.net — manage a nodejs app.